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  • Title: Interaction of psychoactive drugs with the Mg+2 requiring ATPase associated with isolated synaptic vesicles.
    Author: Corbett L, Christian ST, Monti JA, McClain LD.
    Journal: Res Commun Chem Pathol Pharmacol; 1975 Aug; 11(4):605-13. PubMed ID: 241100.
    Abstract:
    A large series of CNS active drugs have been tested for their possible effect on the Mg+2 dependent ATPase associated with isolated synaptic vesicles. Antipsychotic agents and cocaine showed inhibition, of a non-competitive type. The implications of this finding for a synaptic theory of psychosis are discussed.
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