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  • Title: Subglottic stenosis: a ten-year review of treatment outcomes.
    Author: Hseu AF, Benninger MS, Haffey TM, Lorenz R.
    Journal: Laryngoscope; 2014 Mar; 124(3):736-41. PubMed ID: 24122779.
    Abstract:
    OBJECTIVES/HYPOTHESIS: To evaluate the endoscopic surgical management of adult subglottic stenosis and describe treatment outcomes. STUDY DESIGN: Retrospective review. METHODS: Ten-year review of adult patients with subglottic stenosis. RESULTS: Ninety-two adults (23 male, 69 female) with subglottic stenosis underwent 247 endoscopic dilations between 2001 and 2010. The mean age was 48 years at time of first surgery. Etiology was GPA (granulomatosis with polyangiitis, formerly Wegener's granulomatosis) (45%), intubation (25%), or idiopathic (33%). Forty-one patients (45%) underwent a single procedure; 51 patients (55%) required multiple surgeries. The average interval for patients requiring a subsequent procedure was 13.7 months. Variations in surgical technique did not show differences in time to next procedure, and the use of mitomycin-C did not result in longer intervals between procedures. No significant complications were encountered after dilation. CONCLUSIONS: Subglottic stenosis remains a treatment challenge. Although patients are often symptomatically improved after endoscopic dilation, recurrence rates remain high.
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