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  • Title: An in vivo study of the corneal surface in keratoconjunctivitis sicca.
    Author: Lemp MA, Gold JB.
    Journal: Trans Ophthalmol Soc U K (1962); 1985; 104 ( Pt 4)():436-8. PubMed ID: 2412322.
    Abstract:
    Thirteen normal subjects and thirteen subjects with bona fide keratoconjunctivitis sicca were examined employing wide-field colour specular microscopy of the corneal epithelium. The prevalence of small, medium and large cells is different in these two groups with a shift to small cells in patients with keratoconjunctivitis. Increased rose bengal dye uptake filaments, coarse mucus plaques and pre-exfoliative sheets are also seen in keratoconjunctivitis sicca. These findings suggest an accelerated epithelial cell loss from the surface of the eye in keratoconjunctivitis sicca.
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