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  • Title: [Effect of hormonally-induced prolongation of pregnancy in rabbits on maternal and fetal serum lipids].
    Author: Ockert C, Willgerodt H, Keller E, Senger H, Pludra R.
    Journal: Zentralbl Gynakol; 1985; 107(12):744-51. PubMed ID: 2412367.
    Abstract:
    The alterations of the lipid metabolism produced by placental insufficiency were investigated in animal experiments. Pregnant rabbits received Chlormadinon-acetate by intramuscular injection. The pregnancy was prolongated for 4 days, and a placental insufficiency developed. The lipid metabolism of the mothers and the fetuses was investigated by determination of beta-lipoproteides, triglycerides, cholesterol and HDL- and LDL/VLDL-cholesterol. The most important result is an increase of the concentrations of triglycerides and cholesterol of the fetuses during prolongation of pregnancy. Of the different cholesterol fractions estimated the LDL/VLDL-cholesterol-ratio excellently reflects the changes of the lipid metabolism during prolonged pregnancy.
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