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  • Title: Multifocal thoracic chordoma mimicking a paraganglioma.
    Author: Conzo G, Gambardella C, Pasquali D, Ciancia G, Avenia N, Pietra CD, Napolitano S, Palazzo A, Mauriello C, Parmeggiani D, Pettinato G, Napolitano V, Santini L.
    Journal: J Cancer Res Ther; 2013; 9(3):497-9. PubMed ID: 24125991.
    Abstract:
    Chordoma of thoracic vertebras is a very rare locally invasive neoplasm with low grade malignancy arising from embryonic notochordal remnants. Radical surgery remains the cornerstone of the treatment. We describe a case of multifocal T1-T2 chordoma, without bone and disc involvement, incidentally misdiagnosed as a paraganglioma, occurring in a 47-year-old male asymptomatic patient. Neoplasm was radically removed by an endocrine surgeon through a right extended cervicotomy. A preoperative reliable diagnosis of chordoma, as in the reported case, is often difficult. Radical surgery can provide a favorable outcome but, given the high rates of local recurrence of this neoplasm, a strict and careful follow-up is recommended. Although very rare, chordoma should be suggested in the differential diagnosis of the paravertebral cervical masses of unknown origin. Spine surgeon consultation and a FNB should be routinely included in the multidisciplinary preoperative work-up of these neoplasms.
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