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  • Title: Mechanisms of stimulating effect of glycyram and D-glucuronic acid on granulocytopoiesis suppression by 5-fluorouracil.
    Author: Dygai AM, Zhdanov VV, Miroshnichenko LA, Zyuz'kov GN, Udut EV, Simanina EV, Stavrova LA, Khrichkova TY, Reykhart DV, Agafonov VI.
    Journal: Bull Exp Biol Med; 2013 Jun; 155(2):207-11. PubMed ID: 24130991.
    Abstract:
    We compared hemostimulating activity of glycyram and a preparation of D-glucuronic acid on the model of granulocytic hemopoiesis suppressed by 5-fluorouracil. Different mechanisms were shown to underlie activation of hemopoiesis by the above preparations: D-glucuronic acid directly affects hemopoietic cells, while glycyram modulates local mechanisms regulating hemopoiesis.
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