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  • Title: Sympathetic ophthalmia in pediatric age group: clinical features and challenges in management in a tertiary center in southern India.
    Author: Kumar K, Mathai A, Murthy SI, Jalali S, Sangwan V, Reddy Pappuru R, Pathangay A.
    Journal: Ocul Immunol Inflamm; 2014 Oct; 22(5):367-72. PubMed ID: 24131076.
    Abstract:
    PURPOSE: To study the clinical features and visual outcome of sympathetic ophthalmia in pediatric patients attending a tertiary care center. METHODS: Retrospective review of patients ≤16 years with sympathetic ophthalmia seen during the period 2001-2011. RESULTS: During this period, 2511 pediatric patients with open globe injuries and 14 patients with sympathetic ophthalmia were seen. Six patients developed sympathetic ophthalmia during follow-up here. The incidence rate of sympathetic ophthalmia is 0.24% (6/2511, 95% CI:0.05-0.43%). The commonest presenting signs were anterior uveitis and exudative detachment. All patients were treated with systemic steroids, while 7 patients received additional immunosuppressive therapy. Eight patients had a follow-up of more than 6 months. Mean presenting best-corrected visual acuity (1.25 ± 1.03 logMAR) in the sympathizing eye improved significant following treatment (0.42 ± 0.80 logMAR, p = 0.003). CONCLUSIONS: The incidence of sympathetic ophthalmia was 0.24%. Appropriate immunosuppression can lead to favorable visual outcomes in the sympathizing eye.
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