These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


PUBMED FOR HANDHELDS

Search MEDLINE/PubMed


  • Title: Sympathetic stimulation of amylase secretion during a parasympathetic background activity in the rat parotid gland.
    Author: Asking B.
    Journal: Acta Physiol Scand; 1985 Aug; 124(4):535-42. PubMed ID: 2413716.
    Abstract:
    The amylase secretion in vivo was examined in the rat parotid gland. A comparison was made between individual stimulation of sympathetic and parasympathetic nerves and simultaneous activation of both nerves. When sympathetic stimulation was superimposed on a parasympathetic background activity, amylase secretion was elicited at a frequency far below the threshold for secretion of fluid, and increased in a frequency-dependent way. This augmented amylase secretion, seen when the two nerves were activated at the same time, gave an amylase output which far exceeded the sum obtained at individual nerve stimulation. The sympathetic amylase secretion obtained in a background of parasympathetic activity seemed to be dependent entirely on beta 1-adrenoceptors. When high sympathetic stimulation frequency (3-10 Hz) was used a reduction in salivary flow was seen, which was accompanied by a reduced amylase output. This effect was counteracted by alpha-adrenoceptor blockade. Isoprenaline, injected intravenously during an ongoing parasympathetic activity, was found to evoke an augmented amylase secretion in a similar way as sympathetic nerve stimulation.
    [Abstract] [Full Text] [Related] [New Search]