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  • Title: [Interferon-inducing and antiviral effects of inosiplex in combination with high-molecular interferon inducers].
    Author: Tazulakhova EB, Amitina NN, Ershov FI.
    Journal: Biull Eksp Biol Med; 1985 Oct; 100(10):457-9. PubMed ID: 2413924.
    Abstract:
    It has been shown that the immunostimulant inosiplex (IP) is capable of inducing interferon production in mice and of stimulating interferon induction by high-molecular inducers. The combined use of IP and poly (G)-poly (C) or dsRNA (RFf2) leads to a longer interferon circulation in the blood. All the combination schemes ensuring the effect of interferon production prolongation were tested for anti-viral activity. The prophylactic administration of the drugs permitted the attainment in mice of the increased resistance to experimental influenza.
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