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  • Title: Gated ionic channels and the mechanism of excitability.
    Author: Lecar H.
    Journal: Fed Proc; 1985 Dec; 44(15):2941-3. PubMed ID: 2415400.
    Abstract:
    Fluctuating ionic currents caused by the activation of individual ionic channels can be observed in excitable membranes. These single-channel currents allow experimenters to characterize the stochastic properties of the membrane protein conformational transitions that underlie excitation. This exact characterization is leading to a new level of precision in the description of excitable cell behavior throughout the nervous system.
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