These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Inhibition of inositol phospholipid breakdown by D2 dopamine receptors in dissociated bovine anterior pituitary cells.
    Author: Simmonds SH, Strange PG.
    Journal: Neurosci Lett; 1985 Oct 10; 60(3):267-72. PubMed ID: 2415878.
    Abstract:
    Inositol phospholipids have been labelled with [3H]inositol in a lactotroph-enriched preparation of dissociated bovine anterior pituitary cells. Stimulation of cells with thyrotropin-releasing hormone receptor agonists leads to accumulation of [3H]inositol phosphates, and this effect may be inhibited by dopamine (DA) agonists. The DA agonist effect may be prevented by D2 DA receptor selective antagonists. Thus the D2 receptors on these cells are linked to inhibition of inositol phospholipid metabolism, and this provides a functional assay for the receptor.
    [Abstract] [Full Text] [Related] [New Search]