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  • Title: [Effect of steroid hormones on the rate of NADPH and NADH oxidation by rat liver microsomes].
    Author: Sergeev PV, Khalilov EM, Obraztsov NV, Seĭfulla RD.
    Journal: Farmakol Toksikol; 1975; 38(5):600-3. PubMed ID: 241662.
    Abstract:
    Sex hormones heighten the rate of the NADP-H oxidation. A relation between the oxidation rate of steroids and the polarity of their molecule has been found. Both androgens and estogens inhibit the transport of electrons in the NAD-H-dependent chain. The capability of steroids to hydrooxylate depends upon the chemical structure and not the affiliation to androgens or estrogens.
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