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  • Title: [IMP-cyclohydrolase/transformylase from ehrlich-ascites carcinoma (author's transl)].
    Author: Geiger R, Guglielmi H.
    Journal: Hoppe Seylers Z Physiol Chem; 1975 Jun; 356(6):819-25. PubMed ID: 241692.
    Abstract:
    The IMP-cyclohydrolase/transformylase enzyme was purified from Ehrlich ascites tumor cells by ammonium sulfate fractionation and chromatography on Sephadex G-75 and DEAE-Sephadex. The electrophoretically pure enzyme has a molecular weight of about 350000, estimated by a gel filtration, and an isoelectric point of 6.2. It is composed of 8 subunits with a molecular weight of 46000. Every subunit is composed of two different proteins with a molecular weight of 18000 and 28500. Some further characteristics of the enzyme are reported.
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