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  • Title: Anti-actin antibodies. Chemical modification allows the selective production of antibodies to the N-terminal region.
    Author: Benyamin Y, Roustan C, Boyer M.
    Journal: J Immunol Methods; 1986 Jan 22; 86(1):21-9. PubMed ID: 2418119.
    Abstract:
    The specific properties of sera elicited by various native, unfolded or chemically modified actins were compared to provide a means of obtaining high titres of antibodies directed against the N-terminal (1-39) or the central regions of the actin sequence. The antigenic structure of the N-terminal region of actin was analyzed. It has at least 2 discrete epitopes, one of which appears to be species-specific and is composed of the hydrophilic N-terminal heptapeptide sequence.
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