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  • Title: Crystal structure of a left-handed RNA tetramer, r(C-br8G)2.
    Author: Nakamura Y, Fujii S, Urata H, Uesugi S, Ikehara M, Tomita K.
    Journal: Nucleic Acids Symp Ser; 1985; (16):29-32. PubMed ID: 2418421.
    Abstract:
    The crystal structure of the modified RNA tetramer, r(C-br8G-C-br8G), was determined by x-ray methods. The crystals are trigonal and belong to the space group P3212. There are three independent tetramers in the unit cell and each forms a left-handed duplex similar to Z-DNA regarding the orientations of the base moiety and the sugar puckerings in guanosine and cytidine. The effect of the additional bromine atom and 2'-hydroxy group on the stabilization of the Z-form structure are also described.
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