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  • Title: Cardiogenic shock.
    Author: Cooper HA, Panza JA.
    Journal: Cardiol Clin; 2013 Nov; 31(4):567-80, viii. PubMed ID: 24188221.
    Abstract:
    Cardiogenic shock (CS) is a condition in which a marked reduction in cardiac output and inadequate end-organ perfusion results from an array of cardiac insults, the most common of which is acute myocardial infarction. CS is a systemic disease involving a vicious cycle of inflammation, ischemia, and progressive myocardial dysfunction, which often results in death. This life-threatening emergency requires intensive monitoring accompanied by aggressive hemodynamic support; other therapies are tailored to the specific pathophysiology. The development of novel therapeutic strategies is urgently required to reduce the unacceptably high mortality rates currently associated with CS.
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