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  • Title: Cholestatic jaundice as a paraneoplastic manifestation of prostate cancer.
    Author: Kuramoto T, Senzaki H, Koike H, Yamagiwa K, Tamura S, Fujimoto T, Inagaki T.
    Journal: Case Rep Urol; 2013; 2013():303727. PubMed ID: 24191227.
    Abstract:
    Paraneoplastic syndrome associated with prostate cancer is extremely rare. We report a patient who presented with cholestatic jaundice without biliary duct obstruction, hepatic involvement, or infection. After a few detailed examinations, prostate cancer was diagnosed. After treatment with bicalutamide and leuprolide, the patient's symptoms and laboratory abnormalities were reversed. Cholestatic jaundice was regarded as a paraneoplastic manifestation in this patient. The patient remains symptom-free after 14-month followup. Paraneoplastic syndrome should be considered in case of cholestatic jaundice without biliary duct obstruction, hepatic involvement, or infection.
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