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  • Title: Double-stranded regions in denatured DNA from mouse cells.
    Author: Church RB, Georgiev GP.
    Journal: Mol Biol Rep; 1973 Jun; 1(1):21-5. PubMed ID: 24197426.
    Abstract:
    Approximately 2% of the DNA of the mouse genome reassociates at infinitely low C 0 t values, 10(-7) to 10(-6) moles 1(-1) s. The melting profile of the reassociation product, which is resistant to nuclease S1 digestion, has been characterized by hydroxyapatite column chromatography. The properties of these nuclease resistant sequences suggest that they exist as 'DNA-hairpins' and that they originate from reverted base sequences within the genome.
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