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  • Title: [PDT panoramic view. Principle, photosensitizers, light sources and validated indications in dermatology].
    Author: Basset-Seguin N.
    Journal: Ann Dermatol Venereol; 2013 Nov; 140 Suppl 2():223-8. PubMed ID: 24199714.
    Abstract:
    INTRODUCTION: Photodynamic therapy (PDT) combines the use of a topical sensitizer and its excitation with a light of appropriate wavelength. Its use in dermatooncology has been possible in France in 2006 when the methyl ester ALA or Metvixia® got approved. OBJECTIVE: To provide a panoramic view of validated indications of PDT in oncodermatology. METHOD: This work is based on the review of the literature as well as available guidelines or recommendation on PDT in dermatology. RESULTS: Standardized protocols and results of the main clinical trials are given for the three major indications in dermatology: actinic keratosis, basal cell carcinoma and Bowen disease. CONCLUSION: PDT has its role to play in the treatment of multiple superficial carcinomas and cutaneous precancerous lesions and its main advantage resides in its optimal healing.
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