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  • Title: [Determination of alpha-fetoprotein in the serum of pregnant women by rocket-linear immunoelectrophoresis].
    Author: Demchenko TV, Shevtsova AI, Berezin VA, Voronin KV, Usenko LV.
    Journal: Vopr Med Khim; 1986; 32(1):39-42. PubMed ID: 2420066.
    Abstract:
    Rocket-linear immunoelectrophoresis enabled to estimate the alpha-fetoprotein content in blood serum of pregnant women. Sensitivity of the procedure constituted as low as 13-22 ng of the protein per I ml of blood serum. Concentration of the protein in blood serum depended on the period of pregnancy; middle values of normal content of alpha-fetoprotein in blood serum were estimated within various periods of pregnancy in women of the district studied. The procedure might be used simultaneously with immunoenzymatic and radioimmune methods in prenatal diagnosis of impairments in development of the fetus neural tube.
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