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  • Title: Sodium current and gating current experiments on the node of Ranvier.
    Author: Meves H.
    Journal: Biomed Biochim Acta; 1986; 45(1-2):S33-8. PubMed ID: 2421717.
    Abstract:
    Sodium tail currents of the frog node of Ranvier were recorded at different postpulse potentials. Inactivation was inhibited with chloramine-T. At E greater than -60 mV the tail currents decayed with two time constants, tau 1 and tau 2, reflecting presumably the turning-off and the inactivation of the sodium permeability. In the potential range -42 to -12 mV tau 1 (thought to equal tau m off) was not significantly different from the time constant of the turning-on of sodium activation m, tau m on. Similarly, no significant difference between tau on and tau off of the gating current was found if both were measured at the same potential.
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