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  • Title: Circulating progesterone, progesterone-binding proteins and oestradiol-17 beta concentrations in the pregnant Cape porcupine, Hystrix africaeaustralis.
    Author: van Aarde RJ, Potgieter HC.
    Journal: J Reprod Fertil; 1986 Mar; 76(2):561-7. PubMed ID: 2422368.
    Abstract:
    Circulating concentrations of progesterone, progesterone-binding plasma proteins (PBPP) and oestradiol-17 beta in pregnant porcupines remained relatively low until Days 25-30 post coitum. Progesterone values peaked (102-180 ng/ml; N = 3) 42-60 days post coitum and the rapid increase in oestradiol-17 beta concentrations approximated that of progesterone with peak values (170-210 pg/ml) being attained 60-85 days post coitum. The pattern of PBPP synthesis, as suggested by circulating concentrations, was closely related to that of plasma progesterone, with values remaining low (less than 20 pmol/ml) until Day 31 post coitum, reaching peak levels at Days 50-56 and Days 73-77 post coitum. The production of PBPP during pregnancy is, as in related New World hystricomorph species, considered to be a mechanism which facilitates a reduction in the rate of progesterone metabolism during pregnancy.
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