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  • Title: Target-induced quenching for highly sensitive detection of nucleic acids based on label-free luminescent supersandwich DNA/silver nanoclusters.
    Author: Wang G, Zhu Y, Chen L, Wang L, Zhang X.
    Journal: Analyst; 2014 Jan 07; 139(1):165-9. PubMed ID: 24244937.
    Abstract:
    Luminescent silver nanoclusters (AgNCs) were anchored by designed oligonucleotides, acting as fluorescent labels. They hybridized with specific nucleic acid targets to form a supersandwich structure resulting in the fluorescence intensity of the DNA/AgNCs decreasing linearly with respect to the concentration of the target DNA.
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