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  • Title: Spontaneous resolution of lupus nephritis following withdrawal of etanercept.
    Author: Yahya TM, Dhanyamraju S, Harrington TM, Prichard JW.
    Journal: Ann Clin Lab Sci; 2013; 43(4):447-9. PubMed ID: 24247804.
    Abstract:
    INTRODUCTION: Etanercept, a systemic inhibitor of α-TNF, is used for treatment of various autoimmune disorders. We report a case of spontaneous resolution of etanercept-induced lupus nephritis. CASE DESCRIPTION: A 57-year-old female patient taking etanercept for psoriasis presented with laboratory-and histology-confirmed lupus nephritis. After stopping etanercept, there was normalization of proteinuria, hematuria, serum complements, anti-dsDNA antibody, and resolution of the acute glomerular inflammatory process on repeat kidney biopsy. CONCLUSION: This case demonstrates serology- and biopsy-confirmed resolution of active lupus nephritis upon withdrawal of etanercept.
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