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  • Title: A mouse monoclonal antibody against a polymorphic determinant in a defined subset of DR molecules.
    Author: Mazzilli MC, Tanigaki N, Cascino I, Costanzi Porrini S, Trabace S, Cappellacci S, Testa L, Gandini E.
    Journal: Hum Immunol; 1986 Jun; 16(2):148-56. PubMed ID: 2424872.
    Abstract:
    The hybridoma technique was used to produce a mouse monoclonal antibody, designated as XI 21.4, which belongs to the IgG2a class. It is active in complement-dependent cytotoxicity and detects a B-cell antigenic determinant associated with DR1, DR4, DRw10, and, possibly, DRw9. Microfingerprinting of the immunoprecipitate from a homozygous DR4 cell line shows a typical alpha DR pattern and a beta pattern coinciding with that of DR4 molecules.
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