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  • Title: Additive induced core and corona specific dehydration and ensuing growth and interaction of Pluronic F127 micelles.
    Author: Dey J, Kumar S, Nath S, Ganguly R, Aswal VK, Ismail K.
    Journal: J Colloid Interface Sci; 2014 Feb 01; 415():95-102. PubMed ID: 24267335.
    Abstract:
    Pluronic F127 is considered to be the most prominent member amongst Pluronics owing to its uses in the fields of drug delivery and fabrication of mesoporous materials. Though extensive studies were carried out on the phase behavior of this copolymer, the effect of additives on restructuring and growth processes of its micelles is not understood yet. In this manuscript we report DLS, SANS, fluorescence and rheological studies on the effects of NaCl and butan-1-ol on the properties of Pluronic F127 micelles in the aqueous medium. The studies show that corona specific micellar dehydration by NaCl induces inter micellar attraction and consequent formation of micellar clusters. Core specific micellar dehydration by butan-1-ol on the other hand, brings about sphere-to-rod micellar shape transition on approaching the cloud point of copolymer solutions. A room temperature sphere-to-rod shape transition of Pluronic F127 micelles can also be induced in the combined presence of butan-1-ol and NaCl. Observation of such micellar shape transition in aqueous Pluronic F127 system is first of its kind, which can have important bearing with their application in mesoporous structure formation and drug delivery.
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