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  • Title: Gastroduodenal perforation.
    Author: Nirula R.
    Journal: Surg Clin North Am; 2014 Feb; 94(1):31-4. PubMed ID: 24267494.
    Abstract:
    The cause and management of gastroduodenal perforation have changed as a result of increasing use of nonsteroidal antiinflammatories and improved pharmacologic treatment of acid hypersecretion as well as the recognition and treatment of Helicobacter pylori. As a result of the reduction in ulcer recurrence with medical therapy, the surgical approach to patients with gastroduodenal perforation has also changed over the last 3 decades, with ulcer-reducing surgery being performed infrequently.
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