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  • Title: Occupational exposure to ionizing radiation and risk of breast cancer in Western Australia.
    Author: Buitenhuis W, Fritschi L, Thomson A, Glass D, Heyworth J, Peters S.
    Journal: J Occup Environ Med; 2013 Dec; 55(12):1431-5. PubMed ID: 24270294.
    Abstract:
    OBJECTIVE: To evaluate current breast cancer risk due to occupational exposure to ionizing radiation. METHODS: We analyzed data from the Western Australian population-based Breast Cancer Employment and Environment Study. The Breast Cancer Employment and Environment Study included 1205 cases with incident breast cancer during 2009-2011 and 1789 controls. Age-adjusted odds ratios (ORs) were estimated with logistic regression models. RESULTS: There was a weak, not statistically significant association between breast cancer and occupational exposure to ionizing radiation (OR = 1.16; 95% confidence interval, 0.86 to 1.57). The risk of human epidermal growth factor receptor 2-positive breast cancer with occupational exposure to ionizing radiation in women who were premenopausal at the time of interview was higher (OR = 2.57; 95% confidence interval, 1.09 to 6.03). CONCLUSIONS: This study suggests that the risk of breast cancer is low at current levels of occupational exposure to ionizing radiation, although the risk of human epidermal growth factor receptor 2-positive cancer may be a concern.
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