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  • Title: [Combination of missile-induced hypertensive intra-aortic infusion chemotherapy in a patient with hepatocellular carcinoma].
    Author: Takahashi Y, Ueno M, Mai M, Ogino T, Ueda H, Kitamura T, Sawaguchi K, Ohta T, Asai T, Suga T.
    Journal: Gan To Kagaku Ryoho; 1986 Aug; 13(8):2663-6. PubMed ID: 2427034.
    Abstract:
    A case of hepatocellular carcinoma was treated with anti-alpha-fetoprotein (AFP) antibody-adriamycin via the hepatic artery with induced hypertension by angiotensin II. A minor response was achieved (from 13.5 X 9.0 cm to 10.5 X 7.5 cm) and serum AFP decreased from 310,000 ng/ml to 26,000 ng/ml. The patient has been doing well during a follow-up period of one year. This result suggests that targeting chemotherapy used for each drug delivery system would be more effective if combined with two or more similar modalities.
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