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  • Title: Pulchranins B and C, new acyclic guanidine alkaloids from the Far-Eastern marine sponge Monanchora pulchra.
    Author: Makarieva TN, Ogurtsova EK, Korolkova YV, Andreev YA, Mosharova IV, Tabakmakher KM, Guzii AG, Denisenko VA, Dmitrenok PS, Lee HS, Grishin EV, Stonik VA.
    Journal: Nat Prod Commun; 2013 Sep; 8(9):1229-32. PubMed ID: 24273853.
    Abstract:
    New marine natural products, pulchranins B and C (2 and 3), were isolated from the marine sponge Monanchora pulchra and their structures were established using NMR and MS analysis. Compounds 2 and 3 were moderately active as inhibitors of TRPV1 (EC50 value of 95 and 183 microM, respectively) and less potent against TRPV3 and TRPA1 receptors.
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