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  • Title: Theory and experiment on particle trapping and manipulation via optothermally generated bubbles.
    Author: Zhao C, Xie Y, Mao Z, Zhao Y, Rufo J, Yang S, Guo F, Mai JD, Huang TJ.
    Journal: Lab Chip; 2014 Jan 21; 14(2):384-91. PubMed ID: 24276624.
    Abstract:
    We present a theoretical analysis and experimental demonstration of particle trapping and manipulation around optothermally generated bubbles. We show that a particle located within 500 μm of a surface bubble can be attracted towards a bubble by drag force resulting from a convective flow. Once the particle comes in contact with the bubble's surface, a balance between surface tension forces and pressure forces traps the particle on the bubble surface, allowing the particle to move with the bubble without detaching. The proposed mechanism is confirmed by computational fluid dynamics simulations, force calculations, and experiments. Based on this mechanism, we experimentally demonstrated a novel approach for manipulating microparticles via optothermally generated bubbles. Using this approach, randomly distributed microparticles were effectively collected and carried to predefined locations. Single particles were also manipulated along prescribed trajectories. This bubble-based particle trapping and manipulation technique can be useful in applications such as micro assembly, particle concentration, and high-precision particle separation.
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