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Title: FACT and the H2B N tail. Author: Osley MA. Journal: Mol Cell Biol; 2014 Feb; 34(3):300-2. PubMed ID: 24277935. Abstract: The FACT histone chaperone/nucleosome reorganization factor plays key roles in nucleosome dynamics during transcription. A new study has linked a specific domain in the H2B N terminus to the activity of FACT in regulating nucleosome disassembly at promoters during transcription activation and nucleosome reassembly at coding regions during transcription elongation.[Abstract] [Full Text] [Related] [New Search]