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  • Title: CT-guided core biopsy of malignant lung lesions: how many needle passes are needed?
    Author: Lim C, Lee KY, Kim YK, Ko JM, Han DH.
    Journal: J Med Imaging Radiat Oncol; 2013 Dec; 57(6):652-6. PubMed ID: 24283552.
    Abstract:
    AIM: The study aims to determine the number of needle pass in the CT-guided core needle biopsy (CNB) in making a diagnosis of pulmonary malignancy. MATERIALS AND METHODS: A total of 434 CNB records were retrospectively reviewed. The specimen obtained from each needle pass was put in a formalin container and then labelled for separate histopathological reporting. The patients were divided into five groups according to the total number of needle passes (n = 1, n = 2, n = 3, n = 4 and n ≥ 5). In each of the groups 2-4, it was analysed how many needle passes are required before a plateau in diagnostic yield is achieved. RESULTS: CNB produced 283 true-positive and 23 false-negative diagnosis of malignancy. Cumulative sensitivity significantly (P < 0.05) increased between the first and second as well as the second and the third (if done) needle passes, but not between the third and fourth ones. CONCLUSION: Three coaxial needle passes might be optimal in the diagnosis of lung malignancy.
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