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  • Title: Synthesis, characterization and antibacterial and antifungal evaluation of some para-quinone derivatives.
    Author: Amani AM.
    Journal: Drug Res (Stuttg); 2014 Aug; 64(8):420-3. PubMed ID: 24285402.
    Abstract:
    Some novel Pyrrolo [2,3-f] Indole-3,7-Dicarbonitrile derivatives (1-5) were synthesized using chloranil, malononitrile and anilines. The structures of the newly synthesized compounds were characterized by elemental analysis, FT-IR, (1)H- and (13)C-NMR and mass spectroscopy. These compounds were screened for in vitro antibacterial and antifungal activities against some human pathogenic micro-organisms by employing the disc diffusion technique. Some of the compounds showed moderate to good biological activities when compared with standard drugs.
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