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  • Title: Management of ACCF/AHA Stage C heart failure.
    Author: Adigopula S, Vivo RP, DePasquale EC, Nsair A, Deng MC.
    Journal: Cardiol Clin; 2014 Feb; 32(1):73-93, viii. PubMed ID: 24286580.
    Abstract:
    ACC Stage C heart failure includes those patients with prior or current symptoms of heart failure in the context of an underlying structural heart problem who are primarily managed with medical therapy. Although there is guideline-based medical therapy for those with heart failure with reduced ejection fraction (HFrEF), therapies in heart failure with preserved ejection fraction (HFpEF) have thus far proven elusive. Emerging therapies such as serelaxin are currently under investigation and may prove beneficial. The role of advanced surgical therapies, such as mechanical circulatory support, in this population is not well defined. Further investigation is warranted for these therapies in patients with Stage C heart failure.
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