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  • Title: [Cholelithiasis and cholesterosis of a gallbladder: a comparison of pheno-genetypic characteristics of patients].
    Author: Botvin'ev OK, Ivanchenkova RA, Eremeeva AV.
    Journal: Eksp Klin Gastroenterol; 2013; (4):25-8. PubMed ID: 24294780.
    Abstract:
    A study was and comparison was carried out of the phenotypical and genotypical features in 115 patients with cholelythiasis and 97 patients with cholesterosis of the gallbladder. The received data proves that cholelythiasis is characterized by the domination of (prevalence) of type O I blood type, decrease of blood types B III and AB IV in comparison to the control group and to the group with cholesterosis of the gallbladder (p < 0.05), increase of the frequency of gene O decrease of frequency of gene B, decrease of heterozygosis. Patients with cholesterosis of the gallbladder are characterized by the increase of frequency of gene A, decrease of ratio of patients with blood type B III and increase of patients with AB IV blood type (p < 0.05). The received data (results) show the presence of different and multidirectional phenotypical and genotypical characteristics in patients with cholelythiasis and cholesterosis of the gallbladder, and therefore differ genotypically.
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