These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Sequences containing the Alu elements from a human fibroblast cDNA clone library: nucleotide sequence and expression in various tissues].
    Author: Korneev SA, Maleeva NE, Dzhincharadze AG, Slominskiĭ PA, Ivanov PL.
    Journal: Mol Biol (Mosk); 1986; 20(5):1377-89. PubMed ID: 2430173.
    Abstract:
    Alu containing cDNA clones were isolated from a human fibroblast cDNA library. The nucleotide sequences of two clones were determined. In both cases Alu repeats appeared to be situated in the regions presumably corresponding to the 3'-end of mRNA. The comparison of the unique sequences of those clones did not show any homology between them. Both cDNA clones contained large open reading frames, extending into the Alu regions. DNA of one clone was used as a probe for Northern blot-hybridization analysis of poly(A)+ cytoplasmic RNA from some normal and tumor human tissues. All RNA samples contained Alu-homologous transcripts, mainly in 7-12S fractions and only in one (canonical) orientation. This orientation contained functional regions including promotor region for RNA-polymerase III.
    [Abstract] [Full Text] [Related] [New Search]