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  • Title: Palmoplantar keratoderma in association with myxedema.
    Author: Hodak E, David M, Feuerman EJ.
    Journal: Acta Derm Venereol; 1986; 66(4):354-7. PubMed ID: 2430412.
    Abstract:
    A 63-year-old female who had been suffering from intractable palmoplantar keratoderma for 13 years was found to have myxedema. Shortly after institution of substitution therapy with thyroid hormone there was a striking improvement in her condition. The possibility of a causal relationship between hypothyroidism and hyperkeratosis is suggested.
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