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  • Title: Lysosomal enzymes in peripheral blood lymphocytes of patients with gastric cancer.
    Author: Moszczyński P, Moszczyński P, Sułowicz W.
    Journal: Folia Haematol Int Mag Klin Morphol Blutforsch; 1986; 113(4):460-5. PubMed ID: 2431966.
    Abstract:
    The activity of acid phosphatase, beta-glucuronidase and N-acetyl-beta-glucosaminidase was assessed using semiquantitative cytochemical methods in peripheral blood lymphocytes of 45 untreated patients with gastric cancer and 80 healthy subjects. In cancer patients the study demonstrated a statistically significant decrease in the number of lymphocytes with granular reaction for acid phosphatase and N-acetyl-beta-glucosaminidase, as well as an increase in the number of lymphocytes showing a granular-diffuse reaction for the above enzymes and a diffuse reaction for all the studied lysosomal enzymes. Possible mechanisms of the observed changes are discussed.
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