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  • Title: Bone chips, fibrin glue, and osteogeneration following lateral suboccipital craniectomy: a case report.
    Author: Linsenmann T, Monoranu CM, Kessler AF, Ernestus RI, Westermaier T.
    Journal: BMC Res Notes; 2013 Dec 09; 6():523. PubMed ID: 24321093.
    Abstract:
    BACKGROUND: Suboccipital craniectomy is a conventional approach for exploring cerebellopontine angle lesions. A variety of techniques have been successfully employed to reconstruct a craniectomy. This is the first report about the histological findings after performing a cranioplasty by using a mixture of autologous bone chips and human allogenic fibrin glue. CASE PRESENTATION: A 53-year-old German woman underwent left lateral suboccipital retrosigmoidal craniectomy for treatment of trigeminal neuralgia in 2008. Cranioplasty was perfomed by using a mixture of autologous bone chips and human allogenic fibrin glue. Due to recurrent neuralgia, a second left lateral suboccipital craniectomy was performed in 2012. The intraoperative findings revealed a complete ossification of the former craniotomy including widely mature trabecular bone tissue in the histological examination. CONCLUSION: A mixture of autologous bone chips and human allogenic fibrin glue seems to provide sufficient bone-regeneration revealed by histological and neuroradiological examinations.
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