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  • Title: Self-expandable metal stents for malignant colonic obstruction: data from a retrospective regional SIED-AIGO study.
    Author: Di Mitri R, Mocciaro F, Traina M, Montalbano LM, Familiari L, D'Amore F, Raimondo D, Virgilio C, Tarantino I, Barresi L, Giunta M, Borina E, Borruto A, Marino A.
    Journal: Dig Liver Dis; 2014 Mar; 46(3):279-82. PubMed ID: 24326063.
    Abstract:
    BACKGROUND: Self-expandable metal stents are a non-surgical option for the treatment of symptomatic malignant colorectal obstruction as palliative treatment or as a bridge to surgery. AIMS: To report data from a regional study on self-expandable metal stent (SEMS) placement for malignant colorectal obstruction. METHODS: Two hundred and four patients (male 54.9%, mean age of 69.5 ± 14.2) were retrospectively evaluated and data on technical and clinical success, and complications, were analyzed. RESULTS: Technical and clinical success rates were 99% and 94.6% respectively, with 36.7% treated on an emergency basis and 63.3% electively. Palliative treatment was administered to 70.1%, and as a bridge to surgery for 29.9%. Complications were 17 neoplastic ingrowths, 10 stent migrations, and 4 perforations. Palliative treatment was associated with a higher risk of stent ingrowth (p=0.003), and chemotherapy with a lower risk of stent ingrowth (p=0.009). CONCLUSION: This regional study, although it has certain limitations, confirms the positive role of self-expandable metal stents in the treatment of symptomatic malignant colorectal obstruction, and that chemotherapy decreases the risk of ingrowth.
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