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  • Title: [Allergic encephalomyelitis in guinea pigs on the intracutaneous and subcutaneous administration of fragment 114-122 of the human myelin cationic protein].
    Author: Ishchenko AG, Kovanova NIa, Gorina NA, Maksimov SN, Belova TI.
    Journal: Biull Eksp Biol Med; 1987 Jan; 103(1):92-4. PubMed ID: 2432968.
    Abstract:
    Single intracutaneous injection of 30 micrograms of human basic myelin protein peptide 114-122 (H-Phe-Ser-Trp-Gly-Ala-Glu-Gly-Gln-Arg-OH) with Freund adjuvant induced the onset of encephalomyelitis on day 9-19 after the injection. The lethality was 33%. In autumn the disease was more severe than in summer.
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