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  • Title: [Structural damages and DNA synthesis in bone marrow and peripheral blood cells in myelodepression induced by cytostatic preparations].
    Author: Ishkhanova MA, Moskalenko IP, Grinberg SM, Mitriaeva NA, Ronin VS.
    Journal: Eksp Onkol; 1986; 8(6):67-9. PubMed ID: 2433123.
    Abstract:
    Some structural and functional indices of the genome state of rat myelopoietic cells after cytostatic ingestion are studied by the immunofluorescent method and by 3H-thymidine incorporation. It is shown that administration of cyclophosphamide causes structural and functional damages of hemopoietic cells. It is suggested that the intensity of repair potentials is a leading factor in restoration of depressed hemopoiesis.
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