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  • Title: [The role of genetic factors in the development of chronic dust bronchitis in workers of coal mining enterprises of Kuzbass].
    Author: Gafarov NI, Zakharenkov VV, Panev NI, Kucher AN, Freĭdin MB, Rudko AA.
    Journal: Gig Sanit; 2013; (4):44-7. PubMed ID: 24340601.
    Abstract:
    The distribution of genotypes of HP, GC, EsD, AsP and polymorphisms GSTT1 (GST-theta1) and GSTM1 (GST-micro1) and NOS3 (polymorphism VNTR4) in miners with chronic dust bronchitis, and in those without this occupational disease has been studied The carriers of genotypes of genotypes EsD 1-2, AsP bb were shown to be more prone to develop chronic dust bronchitis. Endogenous factors of resistance to the disease are the genotypes GC 1-1, EsD 1-1, AsP bc.
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