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  • Title: [Comparative evaluation of the anti-arrhythmic activity of carbamazepine, novocainamide and obzidan in ventricular extrasystole].
    Author: Logosha IuI, Kamalova EG, Khusainova FS.
    Journal: Farmakol Toksikol; 1986; 49(6):71-3. PubMed ID: 2434357.
    Abstract:
    Twenty-six patients with different diseases of the myocardium complicated by ventricular extrasystole were studied by means of intermittent 24-hour ECG-monitoring using the "Malysh" apparatus. Control of treatment was performed on the 4th-6th day. Carbamazepine effect was observed in 2/3 of patients and significantly exceeded effects of obzidan and novocainamide. No direct relationship was revealed between pharmacodynamics and pharmacokinetic parameters of carbamazepine.
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