These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Utility of fine-needle aspiration and core biopsy with touch preparation in the diagnosis of renal lesions.
    Author: Scanga LR, Maygarden SJ.
    Journal: Cancer Cytopathol; 2014 Mar; 122(3):182-90. PubMed ID: 24353131.
    Abstract:
    BACKGROUND: Cytologic evaluation by fine-needle aspiration (FNA) and core biopsy (CB) with touch preparation (TP) is used in the diagnosis of renal lesions. METHODS: Consecutive image-guided FNA and CB, with or without TP, of renal lesions were reviewed. The cytology diagnoses were correlated with the radiology, surgical specimens, and clinical course. RESULTS: A total of 154 procedures (76 FNA, 17 FNA+CB, 46 CB+TP, 15 FNA+CB+TP) were performed for lesions with benign (21), malignant (123), or indeterminate (10) radiology. Specimen adequacy was satisfactory in 86% of FNAs (93 of 108), 95% of TPs (58 of 61), and 94% of CBs (73 of 78), and is statistically significant for CB with or without TP versus FNA (P = .045). In the subset with concerning radiology (n = 133), specimen adequacy was satisfactory in 83% of FNAs (72 of 87), 95% of TPs (58 of 61), and 94% of CBs (73 of 78) (P = .006 for CB ± TP versus FNA), and procedures were diagnostic in 79% of FNAs (69 of 87), 90% of 61 TPs (55 of 61) and 90% of CBs (70 of 78) (P = .02 for CB ± TP versus FNA). Renal cell carcinoma subtype was reported in 63% of FNA (19 of 30) versus 88% of CB ± TP (43 of 49) (P = .01), and Fuhrman nuclear grade was reported only on CB. The cytology diagnoses correlated with surgical specimens in 94% (33 of 35). The most common treatment was ablation of small (3.0 ± 1.3 cm) masses (n = 47). CONCLUSIONS: Compared with FNA, CB and TP have higher adequacy and diagnostic yield and provide more diagnostic information. Cytology diagnoses are highly accurate when correlated to surgical specimens.
    [Abstract] [Full Text] [Related] [New Search]