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  • Title: Synthesis and biological evaluation of dehydroepiandrosterone-fused thiazole, imidazo[2,1-b]thiazole, pyridine steroidal analogues.
    Author: Zhang BL, Song LX, Li YF, Li YL, Guo YZ, Zhang E, Liu HM.
    Journal: Steroids; 2014 Feb; 80():92-101. PubMed ID: 24355392.
    Abstract:
    A series of steroidal[17,16-d]thiazole, steroidal[1,2-b]pyridine and steroidal[17,16-d]thiazole[2,1-b]imidazo products were synthesized through a convenient and productive method. Anti-proliferation activity against EC109 (human esophageal carcinoma), EC9706 (human esophageal carcinoma) and MGC-803 (human gastric carcinoma) cell lines was examined in vitro. Among the screened compounds, several highly potential compounds were located.
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