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  • Title: An intravascular large B-cell lymphoma with a t(3;14)(q27;q32) translocation.
    Author: Cui J, Liu Q, Cheng Y, Chen S, Sun Q.
    Journal: J Clin Pathol; 2014 Mar; 67(3):279-81. PubMed ID: 24357441.
    Abstract:
    A 61-year-old man with no symptom was found with bilateral adrenal nodules on CT scan during a routine physical check-up. The left nodule was removed by adrenalectomy, and the patient was diagnosed with intravascular large B-cell lymphoma (IVLBCL) on pathological and immunohistochemical examinations. Using a set of dual-colour, break-apart probes and fluorescence in situ hybridisation, it was revealed that the lymphoma cells have tetraploid karyotype, with a breakpoint in BCL6 gene, which was further confirmed as a t(3;14)(q27;q32) translocation. To the best of our knowledge, this is the first report of IVLBCL with such a translocation.
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