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  • Title: Capsaicin in the treatment of dermatologic disease.
    Author: Bernstein JE.
    Journal: Cutis; 1987 Apr; 39(4):352-3. PubMed ID: 2438089.
    Abstract:
    Capsaicin cream is the first of a class of neuropeptide active agents to be introduced into dermatologic therapy. Capsaicin's effects appear primarily related to its ability to deplete the neuropeptide substance P from local sensory terminals in the skin. The use of capsaicin cream in the treatment of postherpetic neuralgia and psoriasis is discussed. I believe that capsaicin and other neuropeptide active agents may become important therapeutic modalities for the dermatologist in the near future.
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