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  • Title: [Granulosa cell tumor of the ovary: retrospective study of 17 cases].
    Author: Rebstock LE, Leufflen L, Leroux A, Harter V, Verhaeghe JL, Marchal F.
    Journal: Gynecol Obstet Fertil; 2014 May; 42(5):331-3. PubMed ID: 24394321.
    Abstract:
    Granulosa cell tumors of the ovary are rare tumor of ovary, included in the sex cord-stromal tumor category, hormone secreting. Seventeen patients with adult-type granulosa cell tumor were identified between 1995 and 2012. All have received surgical treatment first at stage I. Thirty-three percent of the patients relapsed with peritoneal nodules in 68% of the cases, treated surgically and sometimes with complementary therapies, such as chemotherapy, radiotherapy, hormonal treatment. Overall survival and recurrence-free survival were 100% and 58.3%, respectively at 10 years with median time to recurrence of 6 years (4-27). These tumors have therefore a good prognosis and require long-time follow-up. Finally, the prognostic factors of recurrence identified in the literature are FIGO stage, the presence of residual tumor and tumor size.
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